Further, patients with JIA who received TNF inhibitors and were not exposed to MTX and TNF inhibitors did not present significantly increased TB infection rates (TNF inhibitor group vs. non-JIA cohort: aHR = 5.43; 95% CI: 0.73–40.18; P = 0.097; unexposed group vs. non-JIA cohort: aHR = 1.5; 95% CI: 0.53–4.25; P = 0.445; Table 3). Here, TNF is linked to juvenile idiopathic arthritis.