VLDLR and type 1 diabetes mellitus: In concert with our data, overexpression of the VLDL receptor using a helper-dependent adenovirus resulted in aggressivelowering of triglyceride- and cholesterol-rich lipoproteins, reduced lesion size and reduced intraplaque hemorrhage in a virally-induced transgenic Ldlr-/- mouse model of type 1 diabetes [43].