In addition, in combination with the information from the Disease Ontology database, we found that 12 known primary hepatic cancer (PHC) related genes, including MYC, CDC16, DDR1, EBAG9, IGF2, KDR, MAD2L2, MEF2C, NDRG2, SIX1, TNFRSF10B and TSGA10, were HyperM in the arsenic-exposure group. This evidence concerns the gene DDR1 and liver cancer.