NRAS and Miyoshi myopathy: As regards NRAS and KRAS, a slight enrichment of mutated cases among hyperdiploid MM patients can be observed in both the main WES studies for MM: both NRAS and KRAS were reported mutated in 18.5% of non-hyperdiploid (NHD) and 30% of hyperdiploid (HD) patients in the dataset from Bolli et al. [16], while in the cohort by Lohr et al. [17] NRAS mutations were detected in 16.3% of NHD and 22.4% of HD patients, and KRAS mutations in 18.6% of NHD and 26.7% of HD cases (although association did not reach statistical significance).