A univariate Cox regression analysis revealed that only age (hazard ratio [HR] = 1.036 [95% confidence interval (CI) = 1.002–1.072]; p = 0.039), and NT-proBNP (HR = 1.016 [CI = 1.001–1.033] per 100 pg/ml increment; p = 0.041) and triglyceride (HR = 0.988 [CI = 0.978–0.999]; p = 0.032) plasma levels were associated with a new diagnosis of cancer. This evidence concerns the gene NPPB and cancer.