MTHFR and metabolic syndrome: All MTHFR 3′-UTR minor genotypes (2572CA + AA, 4869CG + GG, 5488CT + TT, and 6685TC +CC) showed RERIOR >0 in combinations with <5.77 ng/mL of plasma FA (the lowest tertile interval), MetS, and HTN (Table 5, Supplementary Tables S4 and S5).