Furthermore, CGA/Cr restored insulin tolerance in these HF-fed mice to a level comparable to that in mice fed a regular diet (RD-Water) [Fig. 3a,i- gray circles versus white squares and Fig. 3a,ii- AUC: 11780 ± 524 in HF-CGA/Cr (gray bar) versus 10191 ± 529 au in RD-water (white bar)]. This evidence concerns the gene INS and hydrops fetalis.