KRAS and cancer: The depletion of glutamine induced G1 phase arrest in breast and prostate cancer cells, while K-Ras-driven cancer cells and transformed cells arrested in either S- or G2/M-phase alone, with the changes triggered by glutamine deprivation (Thornthwaite & Allen 1980, Fu et al. 2003, Saqcena et al. 2013, 2015).