To test whether the human APOC2-based mimetic peptide could rescue hypertriglyceridemia in apoc2 mutant zebrafish, we injected C-II-a or C-II-i, together with a fluorescent dextran tracer, into zebrafish larvae and assessed the vascular content of neutral lipids (using BODIPY staining) at 30 min and 6, 30 and 72 h after injection. Here, APOC2 is linked to hypertriglyceridemia.