PTGS2 and amyotrophic lateral sclerosis: Several authors have noted that COX2 is involved in several neurological diseases such as Parkinson’s disease (Teismann et al., 2003), amyotrophic lateral sclerosis (Almer et al., 2001), schizophrenia (Müller et al., 2004) and AD (Pasinetti and Aisen, 1998; Hoozemans and O’Banion, 2005).