Sd78-3′, SNORD78 and GAS5 expression was also detectable in different normal basal prostate epithelium cell lines (PNT2C2, RWPE) prostate cancer cell lines (PC346C, LAPC4, VCAP, LNCAP, 22RV1, PC3, and DU145N) as well as in hepatocellular carcinoma (HEP3B) and colon adenocarcinoma (COLO205) cells demonstrating that SNORD78 processing to sd78-3′ is not restricted to prostate tissue or cells. Here, GAS5 is linked to Familial prostate cancer.