For example, analysis of biopsies from non-small cell lung cancer (NSCLC) patients with acquired resistance to small molecule epidermal growth factor receptor (EGFR) inhibitors displayed MET gene amplifications, epithelial to mesenchymal transition (EMT) as well as a transformation from NSCLC into small cell lung cancer [13]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.