IGF1R and non-small cell lung carcinoma: We then assessed the effect of Src activity on the efficacy of IGF-1R TKIs in a subset of high-pSrc-expressing (A549, H1944, H1975, H292, HCC827) and low-pSrc-expressing (H226B, H226Br, H1299, H460 and Calu-1) NSCLC cell lines based on densitometric quantification of phosphorylated Src blots (Additional file 7: Figure S6).