INSR and non-small cell lung carcinoma: We recently reported substantial levels of phosphorylated IGF-1R at tyrosine 1131 (tyrosine 1158 for IR) or tyrosines 1135 and 1136 (tyrosines 1162 and 1163 for IR) (pIGF-1R, hereafter) and IGF expression in tissue specimens from NSCLC patients [15, 16].