TGFB1 and neoplasm: In addition to TGFβ1, large tumor size (HR = 2.10, 95 % CI: 1.25 to 3.49, p = 0.005) and high SBR grade (HR = 1.97, 95 % CI: 1.16 to 3.36, p = 0.013) were the only factors that independently predicted shorter DMFS in the multivariate model.