MKI67 and breast cancer: In a small case–control study on postmenopausal women who received hormone therapy (HT) (28 receiving HT vs. 28 not receiving HT at the time of BC diagnosis), researchers found that HMD correlated with increased Ki-67 expression in ducts and lobules for both groups, although their data appear to be the only published data supporting a positive relationship between HMD and Ki-67, a result that may be mediated by the use of hormone therapy in those postmenopausal patients [46].