FOXO1 and keratoconus: In the aforementioned report only two of the five reported SNPs; rs2721051 (FOXO1, chr13:41110884) and rs4894535 (FNDC3B, chr3:171995605), actually achieved statistical significance in association with KC with p-values of 3.2E-06 and 1.3E-06 respectively and with an OR of 1.5 for both SNPs.