IL6 and hereditary elliptocytosis: Nevertheless, a recent study has identified a positive correlation between serum IL-6 levels and plasma ammonia levels in cirrhotic patients with OHE and suggested that IL-6 might be involved in the mechanism by which ammonia contributes to the pathogenesis of HE.[44] Secondly, in the current study cohort, only one patient had been diagnosed as cirrhosis by liver biopsy.