In addition, the levels of HGF, MCP-1/CCL2, Eotaxin/CCL11 and Rantes/CCL5 that were all overexpressed in progressive MS patients correlated strongly with EDSS, the classical indicator of clinical disability in MS, while EGF and MIP-1β/CCL4 that were diminished in progressive patients inversely correlated with EDSS. Here, CCL4 is linked to myeloid sarcoma.