VEGFA and myeloid sarcoma: Evidence for the occurrence of neovascularization in MS has been observed by contrast-enhanced MRI in the appearance of “ring enhancement” at the periphery, but not at the center of chronic lesions [61] Another MRI study showed a direct correlation between serum VEGF levels and the magnitude of spinal cord lesions, suggesting that VEGF might be involved in the formation of MS spinal cord lesions [62].