Although the percentage of the EoE transcriptome covered by the ALI data (286/1,607 genes = 18%) was slightly less compared to previous microarray analyses comparing IL-13–treated primary esophageal epithelial cells in standard submerged culture with the EoE-associated gene signature (126/574 genes = 22%) [23], several differences between the two studies are noteworthy. This evidence concerns the gene IL13 and eosinophilic esophagitis.