Similar patterns were observed for the ER+PR− and ER−PR+ subgroups (Table 3; Figure S2A–S2B), with the > 80 mm tumor groups exhibiting borderline significance (ER+PR−, HR 1.253, 95% CI 1.009–1.555, P = 0.041; ER−PR+, HR 1.590, 95% CI 1.012–2.498, P = 0.044). The gene discussed is ESR1; the disease is neoplasm.