For example, cdc2 [17–19] and NFKB2 [20–22] enhance androgen-independent growth, and HMGCS2 [23], PIK3AP1 [24], ABCC4 [25], SLC1A5 [26], CYP3A5 [27] genes are associated with PCa progression. The gene discussed is PIK3AP1; the disease is posterior cortical atrophy.