BCR and B-cell chronic lymphocytic leukemia: Parallel experiments carried out by stimulating purified peripheral blood (PB) normal B cells (n = 4) with soluble and immobilized anti-IgM indicated that miR-132 was up-regulated after 20 hours of BCR stimulation, although with a smaller magnitude compared to immobilized anti-IgM stimulated CLL cells (Figure S2B) [30, 31].