In this context, a significant increase in TP53 acetylation was observed (mean fold change 1.21±0.19; P = 0.0072; Figure 4A–4B) upon anti-IgM stimulation, again with similar trends between UM and M CLL cell samples (P = 0.61). The gene discussed is CD40LG; the disease is B-cell chronic lymphocytic leukemia.