HLA-C and muscular dystrophy: Although central nucleation might be an active marker in muscle regeneration and a common feature in muscular dystrophy (Charge and Rudnicki, 2004; Dubowitz et al., 2013; Folker and Baylies, 2013), we observed only a small proportion of fibers that were positive for embryonic MHC (supplementary material Fig. S2), which is normally expressed transiently during muscle regeneration (Sartore et al., 1982; DiMario et al., 1991; Grady et al., 1997).