DNM2 and X-linked myotubular myopathy: Elevated levels of dynamin 2 are thought to also play a pathological role in human CNM because results from Laporte's laboratory have shown an approximate 1.5-fold increase in dynamin 2 expression in muscle lysates from three XLCNM patients compared with two healthy controls (Liu et al., 2011; Cowling et al., 2014).