Recent reports of human cases of CNM coexisting with cardiomyopathy (Ceyhan-Birsoy et al., 2013; Agrawal et al., 2014; Gal et al., 2015) further highlight the importance of assessing the existence of CNM in skeletal muscles from patients with cardiomyopathy arising from PLN mutations. The gene discussed is PLN; the disease is centronuclear myopathy.