Increased oxidative stress is thought to play a role in ALS pathogenesis, and FUS and TDP-43 cytoplasmic inclusions co-localize with stress granule (SG) markers in ALS patients (Ferrante et al., 1997; Liu-Yesucevitz et al., 2010; Bentmann et al., 2012). This evidence concerns the gene FUS and amyotrophic lateral sclerosis.