IL-6-deficient mice show a high predisposition to diet-induced hepatic steatosis, which is related to defects in the process of fatty acid oxidation (El-Assal et al., 2004; Hong et al., 2004; Kroy et al., 2010; Matthews et al., 2010; Yamaguchi et al., 2010). Here, IL6 is linked to fatty liver disease.