EGR1 and neoplasm: Importantly, genes co-expressed with SLC16A7/MCT2 in human tumours also clustered in oncogenic-related pathways (e.g. PI3K, EGFR, KRAS) and effectors of these signalling pathways were found to bind at the SLC16A7/MCT2 gene locus (e.g. MYC, EGR1, PRDM1).