Accordingly, studies on Asian HCC cohorts (Yong et al. 2013; Oikawa et al. 2013; Zeng et al. 2014; Han et al. 2014) demonstrated frequent SALL4 immunoreactivity, and studies on Western cohorts (Miettinen et al. 2014; Liu et al. 2014) found that SALL4-immunopositive HCCs were rare. Here, SALL4 is linked to hepatocellular carcinoma.