The univariate Cox regression analysis showed that PinX1 expression was an independent prognostic marker for ccRCC patients overall survival (hazard ratio, 0.628; 95% CI, 0.464–0.850; P = 0.003; Supplementary Table S1), and disease-specific survival (hazard ratio, 0.600; 95% CI, 0.433–0.832; P = 0.002; Supplementary Table S1). This evidence concerns the gene PINX1 and nonpapillary renal cell carcinoma.