To examine this possibility, AECs plated on 12-well inserts were infected by PR8 (MOI = 0.5) with or without PHA665752, a c-Met inhibitor, placed over the FBs cultured on 12-well plates, and both apical and basal medium was harvested and combined at 48 h after infection to measure IL-8 and GM-CSF secretion. Here, CXCL8 is linked to infection.