BTG3 and Arthritis: The American Academy of Pediatrics guidelines recommend ophthalmology screening every 3–4 months in children with oligoarticular or polyarticular rheumatoid factor (RF) negative arthritis who are antinuclear antibody (ANA) positive, <7 years of age, and diagnosed with arthritis for ≤4 years since they are at high risk for developing uveitis [14].