ROR1 and B-cell chronic lymphocytic leukemia: However, ROR1 is aberrantly expressed by some B-cell malignancies, e. g., lymphomas, CLL, and t(1;19) B-ALL, and by many solid-tumor malignancies, e. g., adrenal, bladder, breast, colon, lung, pancreas, prostate, ovary, skin, testes, uterus, and neuroblastoma [16–21].