As Kasumi-2 cells were sensitive to ROR1-specific T-cell lysis and were not lysed by autologous CARneg T cells (Fig 5), they were genetically modified with lentivirus particles to introduce mKate red fluorescence protein for sorting transduced cells and enhanced firefly luciferase (ffLuc) [44] for serial non-invasive bioluminescence imaging (BLI) of tumor burden in vivo. Here, ROR1 is linked to neoplasm.