Cancer samples did not have significantly higher expression of CARM1FL or CARM1ΔE15 mRNA compared to benign fibroadenomas (p = 0.21 and p = 0.31, respectively; Fig 5A and 5B), even when stratified by hormone receptor status (p = 0.39, p = 0.30, p = 0.308, for CARM1FL, CARM1ΔE15, and total CARM1, respectively; Fig 5C and 5D). This evidence concerns the gene CARM1 and cancer.