The fact that BRCA1 associated breast cancers are mostly diagnosed as being negative for either classical hormone receptors (estrogen receptor (ER), progesterone receptor (PR)), for human epidermal growth factor receptor-2 (HER2) or for all of them (so called triple negative cases), is considered to be one of the most characteristic features [2,5]. The gene discussed is ERBB2; the disease is breast carcinoma.