Regarding sporadic cancer cases (Fig 2A and 2D) 57 out of 86 (66.3%) stained positive for at least one of the two TRs (i.e. T0052α (50/86) and/or TRβ (19/86)), 12 out of 86 (14.0%) were scored as double positive (i.e. expressing TRα and TRβ at the same time) and 33.7% (29/86) were double negative. Here, THRB is linked to cancer.