We reported that mutations in exons 2 and 3 of the ARH1 gene were detected by in lung adenocarcinoma isolated from ARH1 heterozygous mice and tumors in nude mice injected with ARH1 heterozygous MEFs.32 Six mutations were identified in lung adenocarcinoma of ARH1 heterozygous mice, and another eight mutations were found in tumors from nude mice injected with ARH1 heterozygous MEFs (Tables 1 and 2). Here, LDLRAP1 is linked to lung adenocarcinoma.