TLX2 and systemic lupus erythematosus: Anti-dsDNA-NcX ELISA is also suitable for monitoring disease activity in SLE patients: in a longitudinal analysis of 20 patients over a period of 10 months, changes in Anti-dsDNA-NcX ELISA results correlated significantly with changes in disease activity over time (assessed by mSLEDAI 2000 score), while neither Anti-dsDNA ELISA nor Farr-RIA did reflect these changes (12).