Moreover, kinesin-1 light chain was also detected at the cytoplasmic periphery of the NPC together with capsids by immuonogold, and both overexpression of the C-terminus of kinesin-1 light chain, which is involved in binding to the transported cargo, and RNAi-mediated knockdown of kinesin-1 light chain reduce the amount of disassembled capsids found in the cytoplasm and adenovirus infection (Strunze et al., 2011). The gene discussed is KIF5C; the disease is adenoviridae infectious disease.