KIF5C and adenoviridae infectious disease: Since kinesin-1 heavy chain interacts with Nup358 (Cai et al., 2001), Strunze et al. (2011) studied adenovirus infection in both cells depleted of Nup358 by RNAi and cells overexpressing the kinesin-1 heavy-chain, which binds to Nup358 but not to the adenovirus capsid, and found that both conditions reduce adenovirus infection.