TXN and schizophrenia: For patients with schizophrenia, it is shown that in the first psychotic episode, plasma levels of α-tocopherol (Dadheech et al., 2008), ascorbic acid decrease (Suboticanec et al., 1990; Dadheech et al., 2008), level of thioredoxin increases (Zhang et al., 2009; Owe-Larsson et al., 2011).