While ischemia-related changes in cellular populations were expected with the stroke lesions, both co-transporters, KCC2 and NKCC1 would be similarly affected by these changes at the three age groups evaluated (i.e., P7 group where no infarct lesions were seen at P18 vs. P10 and P12 where they were commonly detected; see Figure 5). This evidence concerns the gene SLC12A5 and ischemia.