ERBB3 and schizophrenia: Consistent with the results of human studies, mice with selective ErbB3 receptor deletion in oligodendrocytes demonstrate deficits in social interaction and working memory (Makinodan et al., 2012), suggesting that NRG1-ErbB3 signaling in oligodendrocyte might contribute to the pathogenesis of schizophrenia (Makinodan et al., 2012).