PMP22 and Charcot-Marie-Tooth disease: The CMT1A subtype, associated with the PMP22 (peripheral myelin protein 22) gene duplication, is the most common CMT form accounting for approximately 45–50% of all CMT cases, while CMT2 and CMTX1 are less frequent, accounting for about 17–25% and 8–10% of all CMT cases, respectively [1,9].