The only prospective study, a nested case–control study within the EPIC-Norfolk cohort, reported a positive association between uBPA concentrations and incidence of CAD up to 10 years after BPA measurement, with a significant increase in risk of CAD per SD increase in uBPA: OR = 1.11, 95 % CI = 1.00-1.23 [60]. This evidence concerns the gene DST and coronary artery disorder.