TF and acute respiratory distress syndrome: In the sub-group analysis, patients with sepsis-induced ARDS had significantly higher median levels of TF compared with patients without ARDS (1424.5 (1019.9 to 2595.2) pg/ml vs. 916.2 (724.1 to 1618.2) pg/ml, P < 0.001) and compared with sepsis patients (943.5 (786.4 to 992.4) pg/ml, P < 0.001) at the time of diagnosis, however there was no significant difference between septic shock and non-septic shock patients (P > 0.05) (Fig. 1).