As expected, we observed higher serum CD138 concentrations in the Intact Immunoglobulin Multiple Myeloma subset of patients compared to Light Chain Multiple Myeloma patients: mean CD138 values in Intact Immunoglobulin Multiple Myeloma patients was 90.7 ng/mL, whereas 40.2 ng/mL in Light Chain Multiple Myeloma patients (P =0.012). This evidence concerns the gene SDC1 and AL amyloidosis.