RBFOX3 and Cerebral ischemia: Under the pathological conditions that are fatal to the neurons such as in BPRA, cerebral ischemia, and hypoxia and trauma, the NeuN immunoreactivity has been reported to decrease in the injured neurons (Igarashi et al. 2001; Davoli et al. 2002; Cheng et al. 2014; Cui et al. 2014).