HLA-C and asthma: This included a number of autoimmune disorders (autoimmune thyroid disease (p = 2.3e−3), type 1 diabetes (p = 4.77e−4)), chronic inflammatory diseases (asthma (p = 2.1e−4)), antigen process and presentation (p = 1.97e−3) (S3 Fig) cellular activation, differentiation and development (cluster enrichment score 1.8) as well as MHC class 2 immune response (cluster enrichment score 2.28) (Table 2).