NLK and glioblastoma: Chromatin immunoprecipitation using anti-LEF-1 antibody using the lysates from NLK-low GBM cells pulled down the promoter DNAs of both CD44 and YKL40. In contrast, CHIP-PCR results using the lysates from NLK overexpressing cells were negative, suggesting that transcription of CD44 and YKL40 in these cells at least is regulated by NLK.