CD4 and anogenital human papillomavirus infection: Although direct analysis of TH1 vs. TH2 cells within the CD4+ T cell subpopulation in the tissues has not been completely characterized in sites infected with HPV 6/11, IL-10 and TGF-β, which are markers of TH2-like cells, have been shown to be highly expressed in genital warts and laryngeal papillomas [3,8,13,58].