To investigate possible mechanisms by which MAG-ω3 compounds decrease arthritis progression, levels of key pro-inflammatory cytokines including IL-17A, IL-1β, IL-6 and TNFα were measured by specific ELISA on day 22 in plasma derived from control, CFA, CFA + MAG-DHA-, CFA + MAG-EPA- and CFA + MAG-DPA-treated rats. This evidence concerns the gene IL17A and arthritic joint disease.