In this context, protein content or tumor markers within the fluid have been targeted as additional diagnostic discriminators, including β-HCG [6], albumin [7, 8], vascular permeability factor (VPF) [9], transthyretin [10], CEA [11], CA19-9 [12], EZH2 [13] and calretinin [14]. Here, VEGFA is linked to neoplasm.