CD4 and infection: Lastly, in a cohort of 3378 patients with various baseline CD4+ T-cell count, lack of immunological recovery (defined as CD4+ count <120% of baseline level) was an independent predictor of clinical progression even in the subgroup of patients with baseline CD4 <200/μl, when a composite measure was considered (AIDS, serious nADE, and all-cause death), but not for serious nADE or death.[13] This study was not focused on patients with advanced stage of infection at baseline, whose risk of AIDS is greater during the first months of HAART[14].